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Institute of Physical Chemistry, Polish Academy of Sciences
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The Human Resources Strategy for Researchers
23 Jun 2026

Job Information

Organisation/Company
Institute of Physical Chemistry, Polish Academy of Sciences
Department
Team 3 International Centre for Transational Eye Research
Research Field
Biological sciences » Biodiversity
Biological sciences » Biology
Technology » Biotechnology
Researcher Profile
Recognised Researcher (R2)
Positions
Postdoc Positions
Application Deadline
Country
Poland
Type of Contract
Temporary
Job Status
Full-time
Hours Per Week
40
Offer Starting Date
Is the job funded through the EU Research Framework Programme?
Not funded by a EU programme
Reference Number
40/2026
Is the Job related to staff position within a Research Infrastructure?
No

Offer Description

Post-doc position available in the Institute of Physical Chemistry PAS within National Science Center (NSC)   We seek a highly motivated and enthusiastic Postdoctoral Researcher at the Institute of Physical Chemistry, Polish Academy of Sciences. The position is part of the project entitled “Spatial determinants of immunotherapy resistance in cancer”, funded by the NCN (National Science Centre) in cooperation with the SNSF (Swiss National Science Foundation). Our laboratory at IPC PAS/ICTER provides an international and interdisciplinary research environment with close links to genomics, single-cell sequencing, molecular biology, biotechnology, and bioinformatics. The project involves multimodal (transcriptomic and epigenomic) and spatial profiling of tumor infiltrating immune cells using in-house high-throughput single-cell sequencing methods. 

The Institute provides an international and interdisciplinary research environment.

 

Details about the project:

Significant work over the last two decades has increased our understanding of the intricate, and sometimes opposing roles, that the immune system plays in cancer. While robust immune responses are required for sustained protective anti-tumor responses, tumor infiltrating CD8+ T cells which have the potential to control tumor growth, often acquire a dysfunctional state due to chronic antigen exposure in a nutrient depleted, and suppressive tumor microenvironment (TME). T cell dysfunction is characterized by a gradual loss of effector function coupled with increased expression of immune checkpoint receptors, including CTLA4, PD-1, Lag3 and Tim-3. As a consequence, immune-checkpoint therapy (ICI), using blocking antibodies against these receptors, has emerged as an important treatment modality for cancer. ICI has demonstrated unprecedented responses in patients with several types of metastatic tumors that were otherwise refractory to available treatment options. However recent studies show that across all indications only ~13% of patients respond to immunotherapy.

To date, the majority of efforts to understand how cancer immunotherapy restores anti-tumor T cell responses have concentrated on assessing the reactivation of dysfunctional T cells. It was largely thought that the efficacy of checkpoint blockade is mediated by the direct ability of blocking antibodies to bind to co-inhibitory molecules and reverse the state of T cell dysfunction. However, this concept has been challenged with seminal work demonstrating that existing intra-tumoral CD8+ T cells have limited capacity for rejuvenation with a relatively inflexible chromatin landscape, suggesting that the protective effect of ICI is unlikely to be due to reprogramming of dysfunctional T cells. Without a basic understanding of how ICI precisely works we cannot begin to understand why then, in the majority of patients, ICI fails. As such there is great interest in understanding ways to target other immune cells.

To address these questions, we have outlined a series of experiments to analyze the cellular and transcriptional changes associated with tumor infiltrating immune cells. This proposal is highly interdisciplinary implementing single-cell 'omics' strategies and systems immunology approaches to further unravel the players and rules governing immune responses during malignancy. In addition, we plan to develop a suite of computational tools that will allow us to better understand the organization of tumor microenvironment in terms of the cellular composition, spatial arrangement of cells and their communication.

 

Leader  dr Marcin Tabaka, https://tabaka-lab.org

Where to apply

E-mail
rekrutacja@ichf.edu.pl

Requirements

Research Field
Biological sciences
Education Level
PhD or equivalent
Research Field
Technology » Biotechnology
Education Level
PhD or equivalent
Research Field
Technology » Nanotechnology
Education Level
PhD or equivalent
Skills/Qualifications
  • Solid knowledge and familiarity with techniques in Genomics;
  • Familiarity with Next Generation Sequencing;
  • Familiarity with single-cell methods in Genomics;
  • Excellent communication and organizational skills;
  • Ability to work independently and interact effectively in an interdisciplinary team;
  • Proficiency in English, both spoken and written.
Specific Requirements

Ph.D. degree in Biotechnology, Biology, Genomics, Medicine or related quantitative discipline

Languages
ENGLISH
Level
Excellent
Research Field
Biological sciences » Biology
Years of Research Experience
4 - 10

Additional Information

Benefits

We offer a post-doctoral position (full-time employment) in the Institute of Physical Chemistry PAS with a gross salary of Around 9600 PLN gross

per month financed from the NCN  WEAVE-UNISONO

100% of the work time of Postdoc will be devoted to the realization of the proposed project. The offer is for    6 months with possible extension, not exceeding 2028-03-31   

The successful candidate will be eligible for all programs at the IPC PAS, including the IPC PAS Young Scientists competition and the IPC PAS Young Scientists Mobility competition.

Institute provides an opportunity to participate in ERASMUS+ programme.

Eligibility criteria

   

• Ph.D. degree in Biotechnology, Biology, Genomics, Medicine or related quantitative discipline obtained not earlier than 7 years before the engagement in the project (this period might be longer due to family reasons according to NCN rules);

  • Solid knowledge and familiarity with techniques in Genomics;
  • Familiarity with Next Generation Sequencing;
  • Familiarity with single-cell methods in Genomics;
  • Excellent communication and organizational skills;
  • Ability to work independently and interact effectively in an interdisciplinary team;
  • Proficiency in English, both spoken and written.

 

       

  • A post-doc type post is a full-time post, scheduled by the project’s principal investigator for a person who has been conferred a PhD degree in the year of employment in the project or within 7 years before 1st January of the year of employment in the project (for researchers with multiple PhDs, the date of the first PhD award is deemed the reference date). This period may be extended by a time of long-term (in excess of 90 days) documented sick leaves or rehabilitation leaves granted on account of being unfit to work. In addition, the period may be extended by the number of months of a child care leave granted pursuant to the Labour Code and in the case of women, by 18 months for every child born or adopted, whichever manner of accounting for career breaks is preferable. 
  • Additionally, the candidate for the postdoctoral position must meet the following condition: 

a) has obtained a doctoral degree from an entity other than the entity where employment in this position is planned, or has completed at least a 10- month, continuous, and documented postdoctoral fellowship in an entity other than the entity carrying out the project and in a country other than the country where the doctoral degree was obtained;

b) will be employed for a period of no less than 6 months;

c) during the period of receiving this remuneration, will not receive any other remuneration from funds allocated as direct costs of research projects financed under NCN competitions;

d) during the period of receiving this remuneration, will not receive remuneration from another employer under an employment contract, including an employer based outside Poland;

e) during the period of receiving this remuneration, will not receive retirement benefits from the social security system.

      

Selection process

 The Commission will take into account the following criteria and evaluate applications on a point scale:

· Competence for specific tasks in a research project; 

· Previous scientific achievements (publication record); 

· Candidate’s own initiative in research projects.

 Required documents :

· scientific curriculum vitae, including a list of scientific achievements (scholarships, publications, patents, conference presentations, etc.); 

· motivation letter; 

· a scan of the PhD diploma or other document confirming PhD degree     

• The application deadline is on the

15.07.2026   , 12:00 noon

Applications should be sent to rekrutacja@ichf.edu.pl. IMPORTANT! email subject: “Recruitment no     40/2026    ” (emails without this number will not be considered)

• Top candidates can be invited for an online or in-person interview (20-22.06.2026). We reserve the right to contact and reply to only selected candidates.

• The position will be offered to the person with the highest evaluation by the Recruitment Committee.

• The results of the recruitment are planned to be announced on the 31.07.2026.

• Employment will take place in accordance with the provisions of the competition documentation of the National Science Center (NSC) for the Weave-Unisono and Employment policy of the Institute of Physical Chemistry PAS https://ichf.edu.pl/files/csr/ipc-procedures.pdf .

• The incomplete applications may not be considered 

• The results of the competition are made public.

• Candidates who have been issued a negative opinion by the Competition Committee or candidates not selected for employment have the right to appeal against the results of the evaluation. The appeal shall be lodged with the Director of the Institute  within 7 days from the date of receipt of the appropriate information. The decision of the Director of the Institute shall be final.

Appeals should be sent to the following email address: dzgran@ichf.edu.pl.

• If the top candidate does not sign the contract due to the resignation, we reserve the right to choose the next candidate from the ranking list.

Additional comments

By submitting the application you consent to the processing of your personal data in the recruitment process.

The controller of your personal data is the Institute of Physical Chemistry of the Polish Academy of Sciences with its registered office in Warsaw, NIP: 5250008755 (the "Institute"). The Institute will process your data for the purpose of carrying out scientific and research activities, providing services and contact with the Institute, on the basis of a contract (in connection with the performance of the contract or in order to take action on your request before the contract is concluded – Article 6, paragraph 1, letter b) of GDPR), the legitimate interest of the Institute (Article 6, paragraph 1, letter f) of the GDPR) and legal provisions (Article 6, paragraph 1, letter c) of the GDPR) - depending on the circumstances.

You have the right to: request access to your data, receive a copy of it; rectify (correct) it; delete it; limit its processing; transfer it; lodge a complaint to the supervisory body; withdraw your consent for processing at any time (withdrawal of consent does not affect the lawfulness of the processing carried out prior to its withdrawal) or to lodge an objection to data processing. More information is available on the Institute's website.

https://ichf.edu.pl/theme/ichf/pliki/RODO_klauzula_informacyjna.pdf

Procedure for Reporting Internal Violations of the Law and Subsequent Actions together with Protection of Whistleblowers at the Institute of Physical Chemistry of the PAS with its registered address in Warsaw (link)

 

Work Location(s)

Number of offers available
1
Company/Institute
Institute of Physical Chemistry Polish Academy of Sciences
Country
Poland
City
Warsaw
Postal Code
01-224
Street
Kasprzaka 44/52
Geofield

Contact

City
Warsaw
Website
Street
Warsaw, Kasprzaka 44/52
Postal Code
PL-01-224
E-Mail
mtabaka@ichf.edu.pl
Mobile Phone
+48 798 055 335

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